🔹Aging causes a decline in bone mineral density (BMD) and alters bone microarchitecture, leading to weakened bones. This is due to...

🔹Aging is a natural, progressive decline in physiological function, which increases the vulnerability of cells and tissues to oxidative...

🔹The increasing incidence of age-related diseases, such as Alzheimer's, diabetes, cardiovascular disease, and cancer, which are linked...

🔹Vascular Aging and Cardiovascular Diseases: Aging leads to significant arterial changes, including increased arterial stiffness and...

🔹 Gut Microbiota and Longevity: The gut microbiota's composition significantly differs between long-lived species and their...

🔹Lymphatic aging represented by cellular and functional changes is an increased risk factor for geriatric disorders. 🔹Advanced age and...

🔹Bone health relies on a balance between bone formation by osteoblasts and resorption by osteoclasts. Aging can disrupt this balance,...

🔹Cardiac aging is a natural process characterized by cardiomyocyte hypertrophy and dysfunction. 🔹Energy Metabolism Transformation* -...

🔶Brain: 🔹Both proliferative glial cells and post-mitotic neurons can be positive for markers of cellular senescence. 🔹Markers like...

🔹Diet and nutrition play pivotal roles in modulating aging processes, and plant-based diets rich in bioactive phytonutrients may help...

🔹Hydrotherapy has been used for centuries, with roots in ancient civilizations such as Egypt and China. 🔹Historical figures like...

Mechanisms of GLP-1-Based Drugs: The regulation of body weight involves complex interactions between the brain and adipose tissue,...

An overview of the study is summarized in the attached image. Here, I am including the relevant box information from the article that...

*Reproductive aging not only affects the fertility and physical and mental health of women but also accelerates the aging process of...

*Transposable elements (TEs) are essential components of eukaryotic genomes and subject to stringent regulatory mechanisms to avoid their...

*During cellular senescence, there is a marked activation of SASP components. *Apoptosis is a cellular fate quite distinct from cellular...

*Microglial activation triggers inflammatory cascades in the brain, resulting in demyelination and white matter lesions, often...

Membrane-enclosed organelles are a crucial characteristic of eukaryotic cells, facilitating the compartmentalization of specific...

Hallmarks of kidney ageing Genomic Instability, Telomere Shortening, and Epigenetic Alterations These are classified as 'primary'...

Neuron-specific epigenetic patterns are profoundly altered in the aged brain, contributing to impaired gene regulation and ultimately...